stardrop v7.3 (Optibrium)
90
Structured Review
Optibrium
stardrop v7.3
Stardrop V7.3, supplied by Optibrium, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stardrop+v7%2E3/stardrop+v+7+4/pmc11137182-266-3-5
Average 90 stars, based on 1 article reviews
Stardrop V7.3, supplied by Optibrium, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stardrop+v7%2E3/stardrop+v+7+4/pmc11137182-266-3-5
Average 90 stars, based on 1 article reviews
stardrop v7.3 - by Bioz Stars,
2026-10
90/100 stars
Images
1) Product Images from "Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells"
Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells
Journal: Frontiers in Pharmacology
doi: 10.3389/fphar.2024.1394685
Figure Legend Snippet: Computational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. (A) Oral CNS Scoring profile score vs logS of AD-2441 and its analogs, including two currently known control inhibitors, VY-3-249 and VY-3-135. Plot showing the StarDrop V7 (Optibrium, Ltd., Cambridge, United Kingdom)–derived logS versus a multimetric oral CNS profile score. Score composition and importance of each contributor: logS = 0.8, logP = 0.6, logD = 0.6, BBB category = 0.55, BBB log(brain:blood) = 0.55, P-gp category = 0.5, HIA = 0.4, hERG pIC50 = 0.2, 2D6 affinity category = 0.16, 2C9 pKi = 0.16, PPB90 category = 0.1. The size of the circle correlates with the corresponding score or probability. (B) Computational and SPR-based validation pipeline for the discovery of novel ACSS2 inhibitors.
Techniques Used: Control, Derivative Assay, Biomarker Discovery
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Control:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used Derivative Assay:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used Biomarker Discovery:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used Binding Assay:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used Injection:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used Comparison:Article Title: Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells Article Snippet: We then used Article Title: Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth Article Snippet: We then used |